A Cochrane review evaluated 18 milk thistle studies including people with these conditions. The supplement didn’t have much effect on liver disease complications or deaths compared to placebo (inactive) treatment. Many of the studies included in the review were of poor quality.
It contains cynarin, which has been found to increase the production of bile in the liver. This makes detoxification processes in the body more efficient, helping various organs to clear out harmful toxins such as alcohol and other chemicals.
The Food and Drug Administration (FDA) regulate supplements differently to medications and do not require the same rigorous testing for safety that medications have to undergo.
Choline also helps to transport both cholesterol and triglycerides, two fats that need to be sent away from the liver to other parts of the body where they can support other organs.
According to the findings, a higher proportion of individuals in the glycyrrhizin groups showed significant reductions in symptoms in comparison to the control group.
Zinc is an essential trace element that promotes cell division, DNA synthesis, and immune function. Chronic liver disease can lead to zinc deficiency .
Inflammation plays a major role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Some studies have shown that in patients with NAFLD, the inflammatory cytokine TNF-a is an important feature in both insulin resistance and liver fibrosis. TNF-a also increases fatty acids oxidation. However, ginger supplementation has been found to significantly reduce levels of TNF-a in the body, subsequently reducing the risk of developing NAFLD (12).